Villains and Valor is the Expansion to the base game VENOM Assault. In Villains and Valor, VENOM pushes back against the losses they have suffered at the hands for Freedom Squadron by teaming up with a chaotic group of mercenaries known as the Terrornauts. However Freedom Squadron is not out of the game, because the members of Corporal Carnage's Carnage Corps have joined in, bringing essentials and teamwork the like of which VENOM has never seen! The stakes are raised on both sides, making every battle more intense and the outcome more important.

The addition of Teamwork abilities to Freedom Squadron allow you to actively help out your fellow teams on their turns. Meanwhile, VENOM's addition of the Terrornauts brings about new levels of difficulty for each combat, bringing in failed results, and bonuses to VENOM. New missions take advantage of each sides' abilities, and expand to all new levels.